RECENT ADVANCES IN PLANT-BASED ANTIOXIDANTS: PHYTOCHEMICAL PATHWAYS AND THERAPEUTIC POTENTIAL

Abstract

Plant-based antioxidants, derived primarily from polyphenols, flavonoids, alkaloids, and vitamins, have gained immense scientific interest due to their protective roles against oxidative stress-related diseases such as cancer, cardiovascular disorders, and neurodegeneration. This article reviews recent advances in understanding the biosynthetic pathways of plant-derived antioxidants and their mechanisms of action. It highlights emerging analytical techniques for antioxidant profiling, explores key medicinal plants native to South Asia, and examines preclinical and clinical evidence of therapeutic efficacy. The paper also discusses challenges in bioavailability and proposes strategies for future translational research.